Couperus LE, et al. - Researchers examined 139 orthotopic liver transplantation (OLT) recipients (53 ± 12 years, 76% male), to evaluate how mildly increased right ventricular (RV) afterload impacts long-term outcomes following OLT relative to RV function. Invasive or echocardiographic evaluation of preoperative RV afterload was carried out, which was used to define participants as normal, high-normal (mean pulmonary artery pressure [PAP] 20–25 mmHg or echocardiographic systolic PAP 35–40 mmHg) or mildly elevated (mean PAP 25–35 mmHg or systolic PAP 40–50 mmHg). Increased hemodynamic complications and worse long-term survival were evident in relation to increased RV afterload among the participants. In patients with increased RV afterload, right ventricular function was in the normal range and not related to postoperative outcome.