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Prognostic impact of carotid intima-media thickness and carotid plaques on the development of micro- and macrovascular complications in individuals with type 2 diabetes: The Rio de Janeiro type 2 diabetes cohort study

Cardiovascular Diabetology Jan 16, 2019

Cardoso CRL, et al. – Researchers evaluated the relationships between parameters of carotid atherosclerosis and the future occurrence of micro- and cardiovascular complications in individuals with type 2 diabetes in this study. They assessed 478 participants who were followed-up for a median of 10.8 years for their ultrasonographic parameters of carotid atherosclerosis, intima-media thickness, and plaques at baseline. During follow-up, they found that 116 individuals had a cardiovascular event and 115 individuals died (56 from cardiovascular disease). Furthermore, 131 had newly-developed or worsened diabetic retinopathy, 156 achieved the renal composite outcome (94 newly developed microalbuminuria and 78 deteriorated renal function), and 83 had newly-developed or worsened peripheral neuropathy. Overall, carotid atherosclerosis parameters predicted cardiovascular and renal outcomes, and offered renal risk stratification improvement. The researchers suggested that ultrasonographic carotid imaging may be useful for the management of type 2 diabetes.

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