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Prognostic impact of atrial fibrillation in cardiogenic shock complicating acute myocardial infarction: A substudy of the IABP-SHOCK II trial

Clinical Research in Cardiology Nov 16, 2017

de Waha S, et al. - Researchers sought to determine the prognostic impact of atrial fibrillation (AF) in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI). They found that in this group of patients, there was no association of AF with clinical outcome at 30 days and 12 months.

Methods

  • A substudy of the IABP-SHOCK II trial was performed, wherein, patients were categorized according to the presence or absence of AF.
  • All-cause mortality at 30-day follow-up was the primary endpoint.
  • All-cause mortality, recurrent myocardial infarction, repeat revascularisation, and stroke at 12 months were secondary endpoints.

Results

  • A total of 600 patients were initially enrolled in the IABP-SHOCK II trial, of those, 28.2% (n = 169) had AF.
  • Between patients with and without AF (p=0.81, p=0.74), no significant differences were evident in terms of mortality at 30 days and 12 months.
  • Similarly, there was no difference between the groups in terms of the rates of recurrent myocardial infarction, repeat revascularisation, and stroke (all p > 0.05).
  • In addition, findings demonstrated that there was no interaction of intraaortic balloon counterpulsation (IABP) and no IABP in patients with or without AF with respect to clinical outcome at 30 days and 12 months (p > 0.05).

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