Prognostic factors of oligometastatic non-small-cell lung cancer following radical therapy: A multicentre analysis
European Journal of Cardio-Thoracic Surgery May 24, 2020
Opitz I, Patella M, Payrard L, et al. - Given that therapy with curative intent may benefit patients with oligometastatic non-small-cell lung cancer (NSCLC), researchers sought the prognostic factors linked with better prognosis in a multicentre analysis of patients who underwent surgery of primary tumors in combination with radical treatment of all metastatic sites. The records of oligometastatic patients who underwent resection of primary tumors at 4 centers (August 2001–February 2018) were retrospectively reviewed. Treatment was provided to 124 patients; of these, 72 (58%) were men, mean age 60 ± 9.8 years, with 87 (70%) adenocarcinoma. Brain metastases were identified most commonly (n = 76; 61%) followed by adrenal (n = 13; 10%) and bone metastases (n = 12; 10%). Systemic therapy was provided to 101 (82%) patients. Per outcomes, selected oligometastatic NSCLC may be safely treated with curative intent, including resection of the primary tumor, and with excellent 5-year survival rates, especially in younger patients with pN0 disease.
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