Fernández-de-Misa R, Hernández-Machín B, Combalía A, et al. - Among 108 patients, the median age at diagnosis was 58 years, with primary cutaneous anaplastic large cell lymphoma (PCALCL), researchers identified prognostic factors for specific survival. They retrospectively reviewed individuals with PCALC diagnosed from May 1986 to August 2017 in 16 University Departments using the convenience sampling method. All of the study participants exhibited T1-3N0M0 stages. The authors discovered that 70% of the cases presented with a solitary lesion, mostly at the limbs. After first-line treatment, the complete response rate was 87% and no advantage was found for any of them (surgery, radiotherapy, chemotherapy or other approaches). They observed that 11% and 2%, respectively, were nodal and visceral progression rate. An independent predictive parameter for shorter survival was nodal progression. In individuals with PCALCL, multiple cutaneous lesions at presentation, early skin relapse and nodal progression exhibit worse prognosis.