Chu SE, Seak CJ, Su TH, et al. - Researchers examined the prognostic value of the Systemic Inflammatory Response Syndrome (SIRS) criteria and the quick Sequential Organ Failure Assessment (qSOFA) score for ED patients with influenza. In this single-center, retrospective cohort study, they included data from 3,561 patients (age ≥ 18 at admission) with laboratory-proven influenza. Among these patients, they noted overall in-hospital mortality of 2.7% (95 patients). When the qSOFA scores were 0, 1, 2, and 3, they noted in-hospital mortality percentages of 0.6, 7.2, 15.9, and 25%, respectively. The sensitivity and specificity of 24% and 96.2%, respectively, were noted, when the qSOFA score was ≥ 2. Observations revealed potential utility of the qSOFA score as prognostic predictor for influenza and its possible applicability in the ED as a risk stratification tool. However, due to its poor sensitivity, qSOFA may not be a good screening tool for triage. In influenza, the SIRS criteria had poor predictive value for mortality as an outcome.