Procalcitonin and C-reactive protein as markers of infection in systemic lupus erythematosus: The controversy continues
Lupus Jun 16, 2019
El-serougy E, et al. - Researchers examined serum procalcitonin (PCT) and C-reactive protein (CRP) for their value as markers of infection in systemic lupus erythematosus (SLE) patients. They analyzed serum PCT and plasma high-sensitivity CRP in 69 SLE patients with symptoms and signs of infection and 69 SLE patients without infection. Outcomes revealed a significantly higher level of CRP in SLE patients with infection vs those without infection (median (IQR) 104.5 (25.5–100.9) and 10.3 (5.4–23.1) mg/l, respectively). This confirms the utility of CRP as a marker of infection. However, there were no differences in serum PCT between SLE patients with and without bacterial infection.
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