Stepniak A, et al. – In this review, researchers draw clinicians' attention to the possibility of ovarian Burkitt’s lymphoma (BL) occurrence, which may be imperative in the differential diagnosis of ovarian tumours. Primary ovarian BL is an uncommon condition, incorporated into the entity of non–Hodgkin lymphoma. A tumour can occur uni– or bilaterally in the ovaries with significant symptoms such as abdominal pain or a large abdominal mass. Differential diagnosis, based on imaging features and pathological examination of the specimens, is essential for further treatment because of the various aetiology of ovarian tumours. Albeit the most of the patients suffering from ovarian BL underwent surgery after an ovarian tumour had been detected, surgical treatment is not the treatment of choice in patients with ovarian lymphoma. The mainstay of therapy is chemotherapy without further surgery. The prognosis is better if the chemotherapy protocol is more aggressive and followed by prophylactic central nervous system chemotherapy. Nowadays, multi–agent protocols are administered, which improves the survival rate.

Methods

• For this study, they conducted a review of the literature.
• In this study, they searched PubMed and Web of Science databases by using the keywords ‘‘Burkitt’s’’, ‘‘Lymphoma’’, ‘‘Ovarian’’, ‘‘Primary’’, ‘‘Burkitt’s lymphoma’’.
• Only cases with histopathologically confirmed diagnosis of primary ovarian BL were incorporated into this review.

Results

• In this study, they observed total 50 articles, reporting cases with an ovarian manifestation of primary non–Hodgkin’s lymphoma.
• 21 cases with a histopathologically confirmed BL were assessed to compare various manifestations, treatment and prognosis in ovarian BL.