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Primary hyperparathyroidism in Chinese children and adolescents: A single-center experience at Peking Union Medical College Hospital

Clinical Endocrinology Aug 30, 2017

Wang W, et al. – A retrospective observational study was designed to summarize the clinical characteristics and the molecular genetics in patients with pediatric primary hyperparathyroidism (PHPT) in China. As per the data, unlike adults with PHPT, most pediatric PHPT were symptomatic. It was noted that rickets/osteomalacia were more common in pediatric patients than in their adult counterparts. Pediatric PHPT patients can be treated successfully with surgical intervention. In addition, genetic screening of the MEN1 and CDC73 genes for mutations should be recommended in pediatric patients due to a relatively high mutation rate.
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