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Preventable clinical and psychosocial factors predicted two out of three recurrent cardiovascular events in a coronary population

BMC Cardiovascular Disorders Feb 12, 2020

Sverre E, Peersen K, Weedon-Fekjær H, et al. - Researchers sought to determine the correlation between potentially preventable factors on major cardiovascular (CV) events (MACE) in an outpatient coronary population from routine clinical practice. In this prospective follow-up study of recurrent MACE, they ascertained the imminent impact of risk factors and a wide range of relevant co-factors recorded at baseline. Inclusion of 1,127 consecutive patients 2–36 months after myocardial infarction and/or revascularization procedure was done. The occurrence of 364 MACE in 240 patients was reported during a mean follow-up of 4.2 years from study inclusion; of these 39 were CV deaths. The multi-adjusted analyses revealed not taking statins as the strongest predictor of MACE, succeeded by physical inactivity, peripheral artery disease, chronic kidney failure, former smoking, and higher Hospital Anxiety and Depression Scale-Depression subscale score. Preventable and potentially modifiable factors discussed were correlated with 66% of the risk for recurrent events. Findings thereby suggest a high risk of recurrent MACE in coronary patients. As potentially preventable clinical and psychosocial factors prognosticate two out of three MACE, they recommend targeting these factors in coronary populations.
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