Prevalence of malignant hyperthermia diagnosis in obstetric patients in the United States, 2003 to 2014
BMC Anesthesiology Jan 28, 2020
Guglielminotti J, et al. - Using data from the National Inpatient Sample (2003–2014), researchers focused on the prevalence of malignant hyperthermia (MH) diagnosis as well as associated factors in obstetric patients in this study run for 12 years. They identified a diagnosis of MH attributable to anesthesia, using the International Classification of Diseases, Ninth Revision, Clinical Modification code 995.86. They found 47,178,322 delivery-related discharges, of those, a diagnosis of MH was documented for 215, resulting in a prevalence of 0.46 per 100,000. A significantly increased risk of MH diagnosis in relation to cesarean delivery was revealed on multivariable logistic regression. A lower prevalence of MH diagnosis was reported in Hispanics vs in non-Hispanic whites, while a higher prevalence was seen in the South vs in the Northeast census regions. According to the findings, MH-susceptibility prevalence was approximately 1 in 125,000 in cesarean deliveries, similar to the prevalence seen in non-obstetrical surgery inpatients. Based on these results, stocking dantrolene in maternity units is justified.
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