Sunde J, Wasickanin M, Katz TA, et al. - In view of recent reports associating endosalpingiosis, traditionally regarded as an incidental pathological finding, with gynecologic malignancies, researchers sought to determine the prevalence of endosalpingiosis via examining all benign appearing adnexal lesions using the Sectioning and Extensively Examining-Fimbria (SEE-Fim) protocol, and investigating the pathology database for the presence of endosalpingiosis, gynecologic malignancy, endometriosis, Walthard nests, and paratubal cysts. The prevalence of endosalpingiosis, endometriosis, Walthard nests, and paratubal cysts were 22%, 45%, 33%, and 42% respectively, using the SEE-Fim protocol; these were substantially higher than previously reported. They observed an increase in all lesions with age except endometriosis which increased until menopause then decreased dramatically. Specimens including ovarian tissue from patients age 51 and older showed ubiquitous prevalence of implantation of at least one lesion type (93%). These findings may aid in determining the origin of ectopic lesions and gynecologic disease risk.