Hartman C, Rennert HS, Rennert G, et al. - A large cohort of Israeli children and adolescents with overweight and obesity was examined for the prevalence of elevated liver aminotransferases (ALT) and additional comorbidities. Assessing data from the medical records of 2‐ to 18‐year‐old children and adolescents, researchers identified 50,418 (10.7%) as being overweight and 70,515 (15.0%) as being obese. A total of 2,245 (7.2%) of children who were overweight and 5,475 (16.8%) of children who were obese exhibited elevated ALT, above 30 IU/L (0.51 μkat/L), suggesting that a high number of individuals with overweight or obesity exhibit presence of abnormally elevated ALT. The children and adolescents with elevated ALT were older, were mostly male, had higher BMI, and more cardiometabolic risk factors, with significantly higher systolic or diastolic blood pressure, total cholesterol and triglycerides, and more than three criteria defining metabolic syndrome.