Ben Ayed H, et al. - Via this cross-sectional study conducted in the two university hospitals (UH) of Sfax, Tunisia on July 2017 with all patients hospitalized for at least 48 hours, researchers ascertained the prevalence of health care–associated infections (HAI) in their UH and described associated risk factors. Among 752 eligible patients, 82 HAI were identified, respiratory tract infections being the most prevalent (36.6%). In multivariate analysis, immune-suppression, diabetes, and malnutrition were the intrinsic risk factors independently associated with HAI. Endotracheal intubation, transfer to another department, parental feeding, tobacco use, as well as surgical wound class contaminated or dirty, and peripheral venous catheter were the extrinsic risk factors. Health care workers may avoid these infections with astute identification of HAI risk factors.