Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: Results from the SLE.E.P.Y cohort study
BMJ Open Oct 26, 2017
Pedrotti E, et al. - Analysts evaluate the occurrence of glaucoma, eyelid, corneal and macular disorders in a cohort of patients with obstructive sleep apnoea (OSA) diagnosed by overnight polysomnography. They aimed to examine the risk factors for the mentioned eye diseases (EDs). The current study showed that the EDs were more prevalent in the patients with OSA than in the general population. Severe Apnoea/Hypopnoea Index level appeared to play a role as the risk factor only for glaucoma.
Methods
- For this research, they designed a cross-sectional cohort study between 2014 and 2015.
- This study was conducted at the unit of respiratory medicine and eye clinic of the University of Verona.
- In this study, total 431 consecutive patients were considered eligible.
- Of these, 87 declined to participate, 35 were untraceable and 13 were deceased.
Results
- Total 296 patients aged 64.5±12.8 years who underwent ophthalmic examination were enrolled in this study.
- Among these participants, 23% were female and 77% were male.
- There was 56% (n=166) prevalence of eyelid disorders, 27% (n=80) of corneal disorders, 13% (n=39) of macular disorders and 11% (n=33) of glaucoma.
- Advancing age was not related to the severity of OSA, while significant differences were found for gender, body mass index, Oxygen Desaturation Index, smoking habit, hypertension and diabetes.
- Severe OSA was significantly connected with glaucoma (OR, 95% CI 1.05 to 5.93, p=0.037).
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