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Prevalence and risk factors of chronic kidney disease in an HIV positive Mexican cohort

BMC Nephrology Sep 30, 2021

Valdivia-Cerda V, Alvarez-Zavala M, Sánchez-Reyes K, et al. - Patients with HIV showed a higher prevalence of chronic kidney disease (CKD), and coinfections as Hepatitis C Virus and Mycobacterium tuberculosis were associated with higher CKD development in them.

  • A longitudinal descriptive study of 120 HIV patients was conducted to determine CKD prevalence and reveal the associated risk factors.

  • CKD prevalence was reported to be 15.8%.

  • A higher risk of hepatitis C virus coinfection was observed in CKD patients, relative risk (RR):5.9; hepatitis C virus infection, RR:4.3; ≥ 30 years old, RR:3.9; C clinical-stage, RR:3.5; CD4+ T cells count < 200 cells/μL, RR: 2.4; and HIV-1 viral load ≥ 100,000 cop/mL, RR: 2.7.

  • Considering detection and prompt management of CKD and coinfections is recommended to prevent the progression as well as to delay renal replacement therapy as long as possible.

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