Prevalence and genotype distribution of cervical human papilomavirus infection in the prevaccination era: A population-based study in the Canary Islands
BMJ Open Sep 30, 2020
Andujar M, Roura E, Torres A, et al. - The female population of the Canary Islands was examined for the prevalence and distribution of HPV types prior to the introduction of HPV vaccines. In addition, clinical and sociodemographic factors were investigated. Between 2002 and 2007, a sample of adult women (aged 18–65 years) of Gran Canaria (GC) and Tenerife (TF) stratified into nine age groups was carried out based on the Primary Health Care database. Researchers contacted the women by postal letter and telephone call and visited them in their primary care center. Completion of a clinical-epidemiological survey and collection of cervical samples for cytological study and HPV detection were performed. Among 6,010 women participants, 3,847 were from GC and 2,163 from TF. The overall prevalence of HPV infection for high-risk types was 13.6% and 11.1%. HPV type most frequently observed was 16 followed by types 51, 53, 31, 42 and 59. They detected HPV types included in the nonavalent vaccine in 54.1% of infected women. Following factors were linked with an increased risk of infection: young ages (18–29 years), the number of sexual partners throughout life, not being married, being a smoker, and having had previous cervical lesions or genital warts.
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