Roca-Oporto C, Cebrero-Cangueiro T, Gil-Marqués ML, et al. - Among solid organ transplant recipients (SOTR), Streptococcus pneumoniae is the leading cause of community-acquired pneumonia, so researchers characterized the rate, traits, and clinical impact of S. pneumoniae nasopharyngeal carriage. At the University Hospital Virgen del Rocío, Seville, Spain, they collected two different pharyngeal swabs samples from 500 patients in winter and spring/summer. The analysis revealed colonization in 26 (5.6%) and 15 (3.2%) patients in winter and spring/summer periods, respectively. Compared with non-colonized patients, colonized SOTRs were more often men and cohabitated recurrently with children. In both studied periods, 35B was identified as the most prevalent serotype. The pneumococcal vaccine PPV23 included 45% of total isolates. Antibiotics like trimethoprim-sulfamethoxazole and macrolides were less active. These findings suggest low pneumococcal colonization in SOTR, and most colonizing serotypes are not incorporated in the pneumococcal vaccines.