Prevalence and causes of infantile nystagmus in a large population-based Danish cohort
Acta Ophthalmologica Feb 26, 2020
Hvid K, et al. - In the present study, the researchers sought to provide a population-based estimate on the prevalence of infantile nystagmus, defined as involuntary, oscillating movements of one or both eyes, and to report the causes in the Capital Region of Denmark. For this investigation, they reviewed medical records of children with infantile nystagmus born in the period January 1, 2010, through December 31, 2017, and living in the Capital Region of Denmark. Participants in the study were 103 individuals with infantile nystagmus. Data reported that the overall infantile nystagmus prevalence was 6.1 per 10,000 live births. Findings revealed that it was higher in premature children (28.4/10 000 live births) than children born at term (4.4/10 000), and highest in children born extremely preterm, (97.3/10 000). The most common cause of infantile nystagmus was ocular disease followed by idiopathic nystagmus, neurological disorders, and genetic syndromes and prematurity without retinopathy of prematurity as the only cause. The most frequent cause of infantile nystagmus with albinism and ocular malformations was the ocular disease. No cause could be found in 1/3 of the patients.
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