Goplen CM, et al. - In this systematic review and meta-analysis, researchers investigated how preoperative opioid use influences postoperative patient-reported outcomes after total joint arthroplasty. Using Ovid, Embase, Cochrane Library, Scopus, Web of Science Core Collection, CINAHL on February 15th, 2018, they identified 6 studies for inclusion (n = 7356 patients); preoperative opioids were prescribed in 24% of the patients. Observations revealed the possibility of worse overall pain and function benefits among patients prescribed preoperative opioids after total joint arthroplasty (TJA) when compared to opioid-naïve patients. However, these patients still benefit from undergoing TJA. Hence they recommend judiciously counseling preoperative opioid users regarding potential postoperative pain and function improvements after TJA.