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Preoperative lumbar epidural steroid injections administered within 6 weeks of microdiscectomy are associated with increased rates of reoperation

European Spine Journal Apr 22, 2020

Bhattacharjee S, Pirkle S, Shi LL, et al. - The impacts of preoperative lumbar epidural steroid injections (LESIs) timing on the rates of recurrent microdiscectomy were evaluated. The PearlDiver national insurance claims database was utilized. Researchers stratified microdiscectomy patients by the timing of their most recent LESI prior to surgery into bimonthly cohorts (0–2 months, 2–4 months, 4–6 months). They performed univariate analyses of reoperation followed by multivariate analyses controlling for risk factors where appropriate. The study population consisted with a total of 12,786 microdiscectomy patients; 1090 (8.52%) received injections within 6 months before surgery. The findings of this study reveal that microdiscectomy conducted within 6 weeks following LESIs was correlated with a higher risk of reoperation, while microdiscectomy conducted more than 6 weeks from the most recent LESI indicated no such correlation with increased risk. Future study into the interaction between LESIs and recurrent disk herniation is required.

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