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Preoperative glycaemic control and long-term survival in diabetic patients after coronary artery bypass grafting

European Journal of Cardio-Thoracic Surgery May 14, 2021

Deo S, Sundaram V, Sheikh MA, et al. - Through analyzing the Veteran Affairs data, researchers sought to assess the correlation of preoperative glycated haemoglobin (HbA1c) and long-term outcome after isolated coronary artery bypass grafting (CABG). They divided veterans with diabetes mellitus and isolated CABG (2006–2018) into 4 groups (I: HbA1c < 6.5%, II: HbA1c 6.5–8, III 8–10% and IV: HbA1c > 10%). The association of preoperative HbA1c and long-term survival was assessed with a multivariable Cox proportional hazards model and reported as hazard ratios (HR). In total, 16,190 patients with diabetes mellitus (mean age 64.9 years, male 98%; insulin dependent 53%) underwent isolated CABG. Preoperative HbA1c > 8% is associated with the increased risk of mortality and adverse cardiac events in patients undergoing CABG.

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