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Preoperative anti-inflammatory treatment of diabetic patients does not improve recovery from cataract surgery when postoperatively treated with a combination of prednisolone acetate and nepafenac

Acta Ophthalmologica Jan 14, 2019

Danni R, et al. - Researchers analyzed 103 patients with diabetes undergoing routine cataract surgery to assess the impact of preoperative anti-inflammatory treatment on recovery from cataract surgery. They observed longer irritation in the eyes without preoperative treatment as compared to those with preoperative treatment. They also noted an increase of 2.2 ± 20.2 μm in central subfield macular thickness at 28 days in eyes without preoperative treatment while it was 0.1 ± 25.2 μm in eyes with preoperative treatment. They did not record any eye with pseudophakic cystoid macular edema (PCME), indicating no impairment in recovery from surgery in cases without preoperative anti-inflammatory treatment. They also observed no risk of PCME in eyes which were treated with combination therapy of prednisolone acetate and nepafenac, postoperatively due to a lack of anti-inflammatory treatment.

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