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Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24-chromosome single-nucleotide polymorphism–based preimplantation genetic testing for aneuploidy

Fertility and Sterility Jun 29, 2018

Simon AL, et al. - In this retrospective study, researchers ascertained in vitro fertilization (IVF) outcomes following 24-chromosome single–nucleotide-polymorphism (SNP)–based preimplantation genetic testing for aneuploidy (PGT-A) and euploid embryo transfer. They analyzed women 20–46 years of age undergoing IVF treatment and identified the potential of SNP-based PGT-A for reducing the negative effects of maternal age on IVF outcomes in cycles with transfer. Findings, in addition, suggested that pregnancy outcomes from single-embryo transfers (SET) cycles are not significantly different from those of double-embryo transfer cycles, supporting the use of SET when transfers are combined with SNP-based PGT-A.
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