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Preeclampsia brings the risk of premature cardiovascular disease in women closer to that of men

Canadian Journal of Cardiology Nov 24, 2019

Langlois AWR, et al. - In the current work, researchers sought to determine if prior preeclampsia brings a woman’s risk of cardiovascular disease (CVD) closer to that of a male counterpart. They performed a population-based cohort study in Ontario, Canada, from 1993 to 2017 including 55,186 women with prior preeclampsia, 110,372 randomly selected age- and region-matched men, and 110,372 similarly selected women who gave birth without prior preeclampsia. Median follow-up of nearly 16 years was performed. (1,193 events; ), men had the highest risk of CVD. Men vs women without prior preeclampsia exhibited the highest risk of CVD (3,706 events vs 1,193 events; 24.3 per 10,000 person-years vs 7.5 per 10,000 person-years). The higher risk was also noted for women with a history of preeclampsia (1,252 events; 16.0 per 10,000 person-years). The likelihood of experiencing CVD was even higher among women with preeclampsia requiring preterm delivery (21.5 per 10,000 person-years). These findings suggest that although significantly higher risk of CVD remains evident among men, a history of preeclampsia, particularly with preterm birth, raises a woman’s risk closer to that of a man.
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