Coussa RG, Binkley EM, Wilkinson ME, et al. - In this retrospective chart review, researchers sought to describe the type and degree of refractive error in a large cohort of patients with autosomal dominant Best vitelliform macular dystrophy (AD-BVMD) compared with an age-similar group with ABCA4-associated Stargardt disease. The sample consisted of consecutive patients with molecularly confirmed AD-BVMD and Stargardt macular dystrophy seen at a single academic centre. In total, 178 eyes from 89 patients with AD-BVMD (35 women, 54 men; mean age 36.6 years) and 306 eyes from 153 patients (94 women, 59 men, mean age 30.2 years) with Stargardt disease were involved in the research. The authors discovered that AD-BVMD patients are predominantly hyperopic, while Stargardt's disease patients are predominantly myopic. The findings provide further proof of BEST1's role in ocular development and growth.