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Predictors of postoperative outcomes in infants with low birth weight undergoing congenital heart surgery: A retrospective observational study

Therapeutics and Clinical Risk Management Jul 13, 2019

Lu C, et al. - Through a retrospective observational study of 114 infants with low birth weight (denotes infants born weighing ≤2.5 kilograms, which includes those born preterm or small for gestational age), the researchers intended to recognize predictors of postoperative outcomes in low-birth-weight infants who underwent congenital heart surgery and build nomograms in order to prognosticate postoperative intensive-care unit (ICU) stay. Operation weight and Society of Thoracic Surgeons–European Association for Cardio-Thoracic Surgery (STAT) risk categories were observed as two variables that were independent predictors in multiple logistic regression analysis of hospitalized death whereas sex, prematurity, birth weight, preoperative stay time in neonatal ICU (NICU), diagnostic classification, and STAT risk categories were 6 variables that were independent predictors in the Cox model of postoperative ICU length of stay. With values of 0.758, 0.604, and 0.716, the concordance-index values were estimated in order to determine the discriminative ability of models of the risk of postoperative cardiac ICU stay, postoperative NICU stays, and total ICU length of stay, which symbolized the probability of true-positive results. Therefore, these findings could assist the clinicians to prognosticate postoperative results and optimize therapeutic strategies.
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