Abrar M, et al. - In this single center study, 74 individuals who received botulinum toxin-A (BTX-A) injections for the first time between the dates of March 2004 to August 2017 were assessed in to order to determine whether a poor response and adverse incidents (voiding dysfunction and urinary tract infection) were predictive for first time BTX-A injections in a patient cohort of refractory idiopathic overactive bladder with detrusor overactivity (DO). Male gender was the only predictor of poor response. Predictors of clean intermittent self catheterisation (CISC) were lower maximum urinary flow rates, male gender, and hysterectomy in females. A heightened risk of UTIs in individuals who performed CISC was noted. In conclusion, male gender was related to a poor response to BTX-A injections and heightened risk of CISC. Lower maximum urinary flow rates and women with hysterectomies were at heightened risk of needing CISC after injection. Performing CISC was correlated with heightened risk of UTI. Moreover, while counselling or choosing individuals, these factors could be beneficial.