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Predictors of longitudinal outcomes for children using long‐term noninvasive ventilation

Pediatric Pulmonology Apr 14, 2021

Bedi PK, DeHaan K, MacLean JE, et al. - Researchers focused on demographic, clinical, as well as technology‐related predictors of long‐term noninvasive ventilation (NIV) outcomes in this 10‐year multicentred retrospective review among pediatric population initiated on long‐term continuous or bilevel positive airway pressure (CPAP or BPAP) in Alberta. This study involved 622 children. A higher probability for NIV cessation because of improvement in underlying conditions was predicted by both younger age and CPAP use. Less chances of continuing NIV were observed in children with upper airway disorders or bronchopulmonary dysplasia, while presence of central nervous system disorders was associated with a higher chance of hospitalizations. A higher risk for NIV declination was shown to be predicted by the presence of obesity/metabolic syndrome and early NIV‐related complications. Overall, long‐term NIV results were impacted by demographic, clinical data, and NIV type, and these are required to be taken into account during initial discussions regarding therapy expectations with families. A better monitoring of at‐risk patients and minimization of adverse outcomes might be achieved by acquiring understanding of factors that may influence long‐term NIV outcomes.

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