Bedi PK, DeHaan K, MacLean JE, et al. - Given that noninvasive ventilation (NIV) is first‐line therapy for sleep‐related breathing disorders and chronic respiratory insufficiency, researchers conducted this 10‐year multicentred retrospective review to determine demographic, clinical, and technology‐related predictors of long‐term NIV outcomes. The sample consisted of children (n = 622) started on long‐term continuous or bilevel positive airway pressure (CPAP or BPAP) in Alberta. Demographic, technology‐related, and longitudinal clinical data have been obtained. Children with upper airway disorders or bronchopulmonary dysplasia were less likely to continue NIV, whereas hospitalizations were more likely to occur in the presence of central nervous system disorders. The prevalence of obesity/metabolic syndrome and complications associated with early NIV predicted a greater risk of decline in NIV. Children with more comorbidities or use of additional therapies needed more hospitalizations and the latter also expected higher risk for being switched to invasive mechanical ventilation or death. Long-term NIV results are influenced by demographic, clinical details, and NIV type and need to be considered during initial conversations with families regarding therapy expectations. Awareness of variables that can influence long-term outcomes of NIV may help to better track patients at risk and minimize adverse outcomes.