Rantala HA, et al. - Researchers undertook this retrospective analysis to examine the factors related to survival in an unselected sample of people (n = 195) who initiated long-term oxygen therapy (LTOT) in Tampere University Hospital from January 1, 2012, to December 31, 2015, and were observed until December 31, 2017. COPD and interstitial lung diseases were found as the most frequent diseases evoking the demand for LTOT. The median survival time was estimated to be 2.2 y. Participants ages > 75 y vs those who were ages ≤ 75 y experienced shorter survival. Factors that were related to impaired survival were a diagnosis of interstitial lung disease, Charlson comorbidity index, and required help in activities of daily living, as revealed in multivariate analysis. Findings revealed great variation in the survival of the people who commenced LTOT. The risk of dying in ∼1 y was observed in participants having interstitial lung disease and those who needed assistance with activities of daily living, this implies that especially these patients should be the focus of advance care planning.