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Prediction of preterm pre-eclampsia according to NICE and ACOG criteria: A descriptive study of 597,492 Danish births from 2008 to 2017

Ultrasound in Obstetrics & Gynecology May 28, 2021

Rode L, Ekelund CK, Riishede I, et al. - Using data from the Danish Health Registry and the Danish Medical Birth Registry, researchers conducted this national study investigating the incidence of preterm preeclampsia. In addition, they determined the proportion of women with risk factors for preeclampsia by the criteria suggested by the National Institute for Health and Care Excellence (NICE) and the American College of Obstetricians and Gynecologists (ACOG) during a 10-year period. Among 597,492 women, 3.2% had development of preeclampsia, 0.7% had preterm preeclampsia < 37 weeks and 0.3% had early-onset preeclampsia < 34 weeks. Overall, there was no change in the incidence of preterm preeclampsia over the last decade in Denmark. Overall, 7.5% of all delivering women fulfilled the NICE criteria and 17.3% fulfilled the ACOG criteria. In the total population, women fulfilling NICE criteria and women fulfilling ACOG criteria identified 48% and 61% of those with preterm preeclampsia, respectively. Per findings, addition of moderate-risk factors could aid in improving prediction according to maternal risk factors.

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