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Prediction of imminent preeclampsia at 35–37 weeks gestation

American Journal of Obstetrics and Gynecology Mar 15, 2019

Ciobanu A, et al. - Researchers studied 15,247 pregnancies from 2 maternity hospitals in England in this prospective observational study, to compare the performance of screening for delivery with preeclampsia at ≤2 and ≤4 weeks after assessment at 35+0–36+6 weeks gestation between the use of percentile cut-offs in placental growth factor alone or the soluble fms-like tyrosine kinase-1/placental growth factor ratio and the competing risks model. They identified 326 pregnancies (2.1%) that subsequently experienced preeclampsia. Outcomes revealed the superior performance of screening for imminent delivery with preeclampsia by the competing risks model when compared to that of placental growth factor alone or the soluble fms-like tyrosine kinase-1/placental growth factor ratio at 35+0–36+6 weeks gestation.
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