Abbott CH, et al. - Researchers conducted secondary analyses of data from a 16-week randomized trial of Attachment-Based Family Therapy and Family-Enhanced NonDirective Supportive Therapy in order to estimate the variation in adolescents’ response to and outcomes from treatment of suicidal thoughts and behaviors. By treatment response and outcomes, adolescents were categorized as nonresponders (15.8%), good responders (57.5%), and partial responders (26.7%). Nonresponders more frequently had higher levels of nonsuicidal self-injury and pessimism and more frequently met diagnostic criteria for major depressive disorder (MDD) vs good or partial responders, after controlling for initial symptom severity. Partial responders vs good responders more frequently met criteria for MDD and had higher perceived burdensomeness. Findings point to heterogeneity in treatment response that may require adapting treatments for adolescents with these pretreatment profiles.