Chung KC, et al. - Researchers performed a secondary data analysis using data from the Wrist and Radius Injury Surgical Trial, a 24-site randomized study of distal radius fracture treatment, in which all fractures are severe enough to warrant surgery, in order to determine predictors of better or worse hand outcomes. The Michigan Hand Outcomes Questionnaire (MHQ) summary score 12 months after treatment was assessed as the primary outcome measure. Pain at enrollment, education, age, and number of comorbidities are the factors which were most predictive of 12-month MHQ score. Specifically, the lowest MHQ scores were noted among participants who had a high school education or less and also reported severe pain. Conversely, the highest MHQ scores were evident among participants with less pain and more education and who were age 87 years or younger with one or no comorbid condition. These findings may aid surgeons to recognize subgroups of patients who may experience similar hand outcomes.