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Predicting Humphrey 10-2 visual field from 24-2 visual field in eyes with advanced glaucoma

British Journal of Ophthalmology Sep 11, 2019

Sugisaki K, Asaoka R, Inoue T, et al. - In this investigation, researchers anticipated Humphrey Field Analyzer Central 10-2 Swedish Interactive Threshold Algorithm-Standard test (HFA 10-2) results (Carl Zeiss Meditec, San Leandro, CA) from HFA 24-2 results of the same eyes with advanced glaucoma. Training and testing HFA 24-2 and 10-2 data sets comprised of 175 eyes (175 patients) and 44 eyes (44 patients) with open advanced glaucoma (mean deviation of HFA 24-2 ≤ −20 dB) respectively. Data reported that the mean (SD) test–retest variability of the HFA 10-2 results in the testing data set was 2.1 ± 1.0 dB, whereas the IP method yielded a PredError of 5.0 ± 1.7 dB. Support vector regression (SVR) provided a smallest PredError (4.0 ± 1.5 dB) among the methods tested. The authors suggested that applying SVR to HFA 24-2 results enabled us to anticipate total deviation values with advanced glaucoma with an error range of around 25% at HFA 10-2 test points of the same eye.
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