Boyd H, et al. - In this nationwide register-based cohort study, researchers assessed the connections between pre-eclampsia and later dementia, overall and by dementia subtype and timing of onset. Study participants were all women with at least one live birth or stillbirth between 1978 and 2015. Findings suggested an association of pre-eclampsia with a higher risk of dementia, especially vascular dementia. It is unlikely that cardiovascular disease, hypertension, and diabetes mediate the relationships to any great degree; this suggests pre-eclampsia and vascular dementia might have underlying mechanisms or susceptibility pathways in common. The link between pre-eclampsia and Alzheimer’s disease was modest, and it might be accounted for by uncontrolled confounding by obesity. They suggested practitioners could offer early attention to modifiable vascular risk factors for dementia in a subset of women by asking about a history of pre-eclampsia.