Roeckner JT, et al. - Researchers performed this systematic review to assess the comparative efficacy of antiseptic formulations employed for preparation of the vagina prior to cesarean delivery in preventing endometritis and other infectious complications. Further, they determined the concentrations of these formulations efficacious for this purpose. They identified 23 studies that comprised 7097 women allocated to the following treatments for reducing the risk of infectious morbidity: povidone-iodine (1%, 5%, 10%), chlorhexidine (0.2%, 0.4%), metronidazole gel, cetrimide, or normal saline/no treatment. Outcomes revealed the highest probability of reducing the risk of endometritis, postoperative wound infections and fever among those having vaginal irrigation with povidone-iodine 1%.