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Potentially inappropriate prescribing in people with dementia: An Australian population-based study

International Journal of Geriatric Psychiatry Jun 14, 2019

Eshetie TC, et al. - People with dementia [(defined as those dispensed a medicine for dementia (cholinesterase inhibitors, memantine or risperidone for behavioural and psychological symptoms of dementia)] were compared to people without dementia regarding the prevalence of potentially inappropriate prescribing (PIP) using the Screening Tool of Older Person's Prescriptions criteria. In this retrospective cohort study, researchers included 8,280 people dispensed medicines for dementia and 41,400 comparisons not dispensed medicines for dementia. People dispensed medicines for dementia had PIP more common than comparisons. In people with dementia, the most common instances of PIP comprised use of anticholinergics, long-term use of high-dose proton pump inhibitors and benzodiazepines. Results thereby emphasize the necessity for optimizing prescribing in people with dementia via effective interventions.
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