Kudou K, et al. - In patients with adenocarcinoma of esophagogastric junction (AEG) and upper gastric cancer (UGC), researchers evaluated if postoperative development of sarcopenia could predict a poor prognosis. Findings revealed a correlation of postoperative development of sarcopenia with poor prognosis in these patients.

Methods

• Researchers assessed postoperative development of sarcopenia 6 months after surgery in patients with AEG and UGC who were judged as non-sarcopenic before surgery.
• Stratification of patients into the development group or non-development group was performed.
• The groups were analyzed in terms of clinicopathological factors and prognosis.

Results

• The development group displayed significantly poorer 5-year overall survival rates vs non-development group (68.0% vs 92.6%, P=0.0118).
• Postoperative development of sarcopenia was noted as an independent prognostic factor for poor overall survival in multivariate analyses (P=0.0237).