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Postoperative cognitive dysfunction after sevoflurane or propofol general anaesthesia in combination with spinal anaesthesia for hip arthroplasty

Anesthesia and Intensive Care Nov 10, 2018

Konishi Y, et al. - In patients undergoing total hip replacement surgery, the incidence of postoperative cognitive dysfunction (POCD) was assesed between those administered sevoflurane vs propofol for maintenance of anesthesia. As decided by the anesthetist, either sevoflurane (n=121) or propofol (n=171) was administered to patients after administration of a spinal anesthetic in order to maintain the processed electroencephalogram (bispectral index, BIS) under 60. In the sevoflurane group vs in the propofol group, a significantly lower mean BIS was noted. However, at any timepoint, no statistically significant link between intraoperative BIS level and the incidence of POCD was observed. Overall, the type of anesthesia used in elderly patients had no strong impact on the incidence of POCD.

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