Jang MS, et al. - Between February 1, 2015, and February 28, 2017, authors investigated the consequences of intraoperative balanced 6% hydroxyethyl starch (HES) 130/0.4 on postoperative blood loss and the coagulation profile among 169 cases during major spine surgery. They observed a significant difference in the total intraoperative transfused crystalloid volume between the 2 groups ie, colloid group, 1.394.6±1.414.0 mL; and crystalloid group, 2.027.3±1.114.1 mL. They recorded no variations in either postoperative transfusion requirement or length of hospital stay between the groups. An independent association of operation time and intraoperative transfusion of packed red blood cells or fresh frozen plasma with postoperative blood loss was also noted. They did not suggest intraoperative colloid administration as a predictive factor.