Tezuka J, Sanefuji M, Ninomiya T, et al. - Given that the optimal timing of cow’s milk (CM) protein exposure is uncertain despite evidence for the protective effects of early regular exposure to peanut and egg proteins against allergies, researchers sought to determine when during the first year of life CM‐based formula consumption becomes correlated with lower CM allergy (CMA) risk. The dataset of the Japan Environment and Children’s Study, a nationwide birth cohort involving over 100,000 mother‐child pairs, was used. Data reported that the prevalence of CMA was 0.23% and 1.03%, respectively, at 6 and 12 months of age. According to findings, regular exposure to formula milk at age 3 months or older is correlated with lower CMA at 12 months old, implying that if the exposure is brief, the effect of very early CM exposure on CMA can vanish. At present, however, the findings of this observational study should not be used for formula recommendation and randomized controlled trials are needed to validate this correlation.