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Positive predictive value of the giant cell arteritis diagnosis in the danish national patient registry: A validation study

Clinical Epidemiology Jul 16, 2020

Hjort PE, Therkildsen P, Nielsen BD, et al. - The present study was conducted to evaluate the positive predictive value (PPV) of the giant cell arteritis (GCA) diagnosis in the Danish National Patient Registry (DNPR). Between January 2012 and December 2017, a sum of 293 patients aged ≥ 50 years with a first-time diagnosis of GCA in the DNPR were enrolled. They conducted sub-analyses including the number of redeemed prescriptions performed temporal artery biopsies, and the number of GCA-related hospital contacts. This research confirms the diagnostic code of GCA in the DNPR. In the DNPR, the overall PPV of GCA was 62%. The findings revealed that requiring redeemed prescriptions of GCs and/or GCA-related hospital contacts elevate the PPV, but also excludes a significant number of GCA patients.

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