Greenberg S, Buys SS, Edwards SL, et al. - Researchers used the Surveillance, Epidemiology, and End Results cancer registry data as well as the Utah Population Database in order to determine the prevalence of people with diagnostic features and/or family cancer history meeting criteria for hereditary breast and ovarian cancer (HBOC) testing. They utilized objectively ascertained genealogy and cancer incidence data to quantify the population-based prevalence of HBOC criteria. Based on diagnostic features, the criteria for testing were met by 21.6% of overall Utah residents with an incident breast cancer diagnosis 2010-2015 and evaluable for family history. The assessment of family history led the proportion to rise to 62.9%. For ovarian cancer, prostate cancer, and for pancreatic cancer, the proportion of cases meeting testing criteria at diagnosis was 94%, 23%, and 51.1%, respectively. Sporadic breast cancer was recognized as possibly a part of the observed high prevalence of family cancer history. Based on these findings, ascertaining the presence of a deleterious mutation in an affected family member, per National Comprehensive Cancer Network guidelines, prior to testing unaffected relatives, appeared significant.