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Population pharmacokinetics and dose optimization of teicoplanin during venoarterial extracorporeal membrane oxygenation

Antimicrobial Agents and Chemotherapy Sep 08, 2017

Wi J, et al. - In this work, researchers developed a population pharmacokinetics (PK) model for teicoplanin, investigated covariates influencing teicoplanin exposure, and suggested an optimal dosing regimen for extracorporeal membrane oxygenation (ECMO) patients. Findings suggested the necessity for doses higher than the standard doses to achieve fast and appropriate teicoplanin exposure during ECMO.
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