Tang Y, Zhang J, Dai F, et al. - In this prospective cohort study, researchers intended to determine if there is an association between sleep disturbances and blood pressure as well as uterine artery Doppler during pregnancy in women with no preexisting hypertension. Participants in the study were women with viable singleton pregnancies reported by ultrasonography at less than 14 weeks of amenorrhoea at the first visit. Between September 1, 2010, and August 31, 2014, 926 individuals were recruited for this research in the outpatient specialist clinics at KK Women's and Children's Hospital in Singapore. They were monitored during their pregnancy, with sleep quality, blood pressure, and uterine artery Doppler assessed at each visit. Shorter sleep duration and poorer sleep efficiency were linked to higher blood pressure, particularly in the first trimester. Sleep duration was found to be negatively correlated with both systolic blood pressure and diastolic blood pressure (DBP), while sleep efficiency was negatively related to DBP only. The prospective study showed that poor sleep quality is significantly linked to higher blood pressure and uterine artery pulsatility index during pregnancy.