Endreffy I, et al. - In total 73 Hungarian hospitalized patients, 32 children and 41 adults, were recruited in the study by the researchers and they underwent plasma assay of L-α-fucosidase-1 (α-L-FUCA-1) activity and its correlation with Sjögren syndrome (SS) and other rheumatic disorders was further assessed. In children and in adults, α-L-FUCA-1 associated with SS. In other rheumatic disorders, α-L-FUCA1 did not exhibit any differential distribution correlated to the particular pathology, however, this trend was radically inverse for patients with SS. Thus, modifications in plasma level of α-L-FUCA-1 were significantly related to SS.