Kaze AD, Musani SK, Bidulescu A, et al. - Researchers intended to determine if there is a connection between plasma biomarkers including leptin, adiponectin, adiponectin‐to‐leptin ratio and high‐sensitivity C‐reactive protein (hsCRP) with the risk of glycemic progression and incident dysglycemia (prediabetes or diabetes) in a community‐based sample of African American (AAs). Data were analyzed from 3,223 candidates without type 2 diabetes at baseline (2000‐2004) who attended ≥ 1 follow‐up visit. Data reported that 46.4% developed glycemic progression (n = 1,495) over a median of 7 years. In this large community‐based cohort of AAs, the findings indicate that high plasma leptin and hsCRP, as well as low adiponectin and adiponectin‐to‐leptin ratio, are linked to higher risks of glycemic progression. The results point to the potential utility of these biomarkers in this high-risk population in predicting and preventing glycemic progression.