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Physiological predictors of peak inspiratory flow using observed lung function results (POROS): Evaluation at discharge among patients hospitalized for a COPD exacerbation

International Journal of COPD Dec 20, 2018

Price DB, et al. – Researchers conducted this retrospective observational study to determine potential predictors of peak inspiratory flow (PIF) for different dry powder inhalers (DPIs) from spirometric parameters and patient characteristics and explore the association between PIF and follow-up events. For this purpose, they assessed, at discharge, 47 patients hospitalized for a COPD exacerbation at Attikon Hospital, Athens, Greece, and found that hypertension (70%) and cardiovascular disease (53%) were the most prevalent comorbidities. They observed no factors supporting the use of surrogate measurements for PIF through device resistance, which could assist in concluding the suitability of the inhaler device type, although PIF measurement was perceived feasible in patients at discharge and relevant to the standard of care in COPD management.

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